Potential biomarker for measuring progress in breast cancer chemoprevention trials

October 29, 2015

The researchers identified 155 Mexican-American women with breast cancer and compared them with 333 women of similar ages without breast cancer. Patients reported their weights at ages 15, 30 and at cancer diagnosis. They also reported weight gain between age 15 and diagnosis.

Unlike research in non-Hispanic white women, which has shown an increased risk for breast cancer in obese postmenopausal women, there was no association between body mass index and breast cancer in Mexican-American women, regardless of menopausal status.

"We know that Hispanic women have a lower incidence of breast cancer, but they continue to be diagnosed with breast cancers that have larger tumor sizes, more advanced cancer stages and poorer prognostic factors, leading to lower survival rates compared to non-Hispanic white women," Sexton said. "There is a real need to continue to try to understand why these disparities exist."

Source: University of Texas Health Science Center