Neoprobe Corporation presents information on Lymphoseek at TERACHEM Symposium

September 04, 2015

The study concludes that the focus of future research should be on finding markers to detect which type of atypical vascular lesions are more likely to lead to an angiosarcoma.

"This is probably where most of the research should be done," Mandrell said. "Anybody who has had radiation has changes in their skin. It was probably radiation in combination with the surgery for the cancer that led to the development of this entity. The main question is, 'Are there special markers or other histological features underneath the microscope that would suggest that an atypical vascular lesion is worse and more likely to develop into an angiosarcoma and another one is not?' That's still not well defined."

The study also concludes that the medical community needs to heighten its surveillance of the skin of patients who have a history of surgery and radiation therapy for breast cancer.

"Even benign-appearing lesions can be serious given that medical history," Mandrell said. "Dermatologists and primary care physicians should be looking at the skin for any changes in this patient population."

Source : Loyola University Health System