Gout incidence lower in women than men: Study

August 27, 2015

Results also found among the purported risk factors for gout, increasing age, obesity, alcohol consumption, diuretic use, and hypertension were independently associated with higher risk of gout incidence in women. However, researchers found only a stronger age effect among women placed them at higher risk factors for gout than men. The age-adjusted relative risk (RR) of gout in post-menopausal women was 4.18 and the RR for gout in women using hormone replacement therapy was 0.24. Other risk factors did not differ significantly between women and men.

"Our study found that higher levels of uric acid in the blood increase the risk gout risk for women in a graded manner," concluded Dr. Choi. The risk of gout among women with serum uric acid levels ??8 mg/dl was 46 times higher than that among women whose levels were <5 mg/dl. However, results show the magnitude of the association between gout and uric acid blood levels among women was significantly lower than for men. "Confirming our results using specific case definitions (observation of urate crystal in joint fluid) would provide to be a valuable contribution to understanding gout incidence in both sexes."

Source: Wiley-Blackwell